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  <titleInfo>
    <title>Modelling The Impact of Screening, Treatment And Underlying Health Conditions on Dynamics of Covid-19</title>
  </titleInfo>
  <name type="personal">
    <namePart>Kilonzi, Jeremiah Savali</namePart>
    <role>
      <roleTerm authority="marcrelator" type="text">creator</roleTerm>
    </role>
  </name>
  <typeOfResource>text</typeOfResource>
  <originInfo>
    <place>
      <placeTerm type="text">Meru</placeTerm>
    </place>
    <publisher>Meru University of Science and Technology</publisher>
    <dateIssued>2025</dateIssued>
    <issuance>monographic</issuance>
  </originInfo>
  <language>
    <languageTerm authority="iso639-2b" type="code">eng</languageTerm>
  </language>
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  <abstract>Coronavirus disease is an infectious disease triggered by severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) that belongs to the family of viruses that cause viral pneumonia.
Despite the spreading of the COVID-19 in Kenya with a positivity of 12.9% as at 26 August 2021,
there was no reliable deterministic Mathematical model that described the dynamics of COVID-19
incorporating underlying health conditions and impact of screening and treatment. In this study, we
propose a SIRS (Susceptible-Infected –Recovered-Susceptible) classical mathematical model which
is modified to incorporate the exposed and the treated individuals where COVID-19 is modelled.
The model stratifies the population into two categories depending whether they have underlying
health conditions or not, and describes disease transmission within or between the groups. Five
compartments are considered in the model for each group that is; Susceptible individuals, exposed
population, Infected individuals, treated population and the Recovered population. The Next
generation matrix method was used to determine the basic reproduction number denoted 𝑅𝑜 of the
proposed model. The results obtained indicates that the Disease Free Equilibrium is locally
asymptotically stable whenever 𝑅𝑜
∗ &lt; 1 and globally asymptotically stable if 𝑅0
∗ ≤ 1. On the other
hand, Endemic Equilibrium it is globally asymptotically stable if 𝑅𝑜
∗ &gt; 1.The results obtained
showed that increasing the rate of screening and treatment on the exposed population and weakening
the disease transmission route between the susceptible, exposed and infected population are crucial
to curb the spread of COVID-19 virus. The Government of Kenya should advocate treatment and
screening of the exposed and infected individuals. Further research should consider incorporating
vaccination. </abstract>
  <note type="statement of responsibility"> Jeremiah Savali Kilonzi</note>
  <note>Includes Reference </note>
  <classification authority="lcc">QA276.18.K3 2024</classification>
  <identifier type="isbn"> </identifier>
  <identifier type="issn"> </identifier>
  <identifier type="uri">https://repository.must.ac.ke/handle/123456789/1481</identifier>
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    <url>https://repository.must.ac.ke/handle/123456789/1481</url>
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    <recordCreationDate encoding="marc">260608</recordCreationDate>
    <recordChangeDate encoding="iso8601">20260608121920.0</recordChangeDate>
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