The effect of purple tea extract activity on selected metabolic syndrome parameters in mice/ (Record no. 88077)

MARC details
000 -LEADER
fixed length control field 02195nam a22002057a 4500
003 - CONTROL NUMBER IDENTIFIER
control field KE-MeUCS
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20220909123740.0
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field 220909b xxu||||| |||| 00| 0 eng d
020 ## - INTERNATIONAL STANDARD BOOK NUMBER
International Standard Book Number
022 ## - INTERNATIONAL STANDARD SERIAL NUMBER
Source
040 ## - CATALOGING SOURCE
Transcribing agency KE-MeUCS
Modifying agency KE-MeUCS
050 ## - LIBRARY OF CONGRESS CALL NUMBER
Classification number
100 ## - MAIN ENTRY--PERSONAL NAME
Personal name Mwangi, Erastus S
245 ## - TITLE STATEMENT
Title The effect of purple tea extract activity on selected metabolic syndrome parameters in mice/
Statement of responsibility, etc Erastus S Mwangi and S. Awuor Wandili
260 ## - PUBLICATION, DISTRIBUTION, ETC. (IMPRINT)
Place of publication, distribution, etc Meru:
Name of publisher, distributor, etc Meru University of Science and Technology.
Date of publication, distribution, etc 2022.
490 ## - SERIES STATEMENT
Series statement MUSTIC2022
520 ## - SUMMARY, ETC.
Summary, etc Metabolic syndrome (MetS) is a cluster of metabolic abnormalities. Prevalence of MetS is documented at 50% and 87.5% in Africa and Kenya respectively. It is managed by combining lifestyle modification and pharmacotherapy. Although Camellia sinensis TRFK306 has been proven to induce weight loss in mice and humans, its effect on metabolic syndrome is yet to be investigated. This study aimed to investigate the effect of Camellia sinensis TRFK306 extract on MetS induced Sprague Dawley male rats. A total of thirty-five, six-weeks-old rats were acclimatized for one (1) week and randomized into 5 groups (n=7). Metabolic syndrome was induced using high- fat fructose diet for eight (8) weeks. Post-hoc statistical analysis using Tukey’s multiple comparison test was used to analyze the effect of freeze-dried extracts of Camellia Sinensis TRFK306 on various markers of metabolic syndrome. Random blood sugar levels revealed significant differences (p = <0.0001), for experimental animals. Oral glucose tolerance results were significant (p = <0.0001). Total serum triglyceride levels was significant (p = <0.0001). Mean serum HDL-C levels revealed significant differences between the normal control and negative control (p = 0.0009), the negative control and low dose test (p = 0.0023), the negative control and high dose test (p = 0.0025) and the negative control and positive control (p = 0.0014). The mean serum LDL-C levels revealed significant difference (p= <0.0001). Camellia Sinensis TRFK306 possessed significant beneficial effects on various markers of metabolic syndrome.
700 ## - ADDED ENTRY--PERSONAL NAME
Personal name Wandili, S. Awuor
942 ## - ADDED ENTRY ELEMENTS (KOHA)
Source of classification or shelving scheme Library of Congress Classification
Koha item type Article
Cataloguer Mercy Musungu
Holdings
Withdrawn status Lost status Source of classification or shelving scheme Damaged status Not for loan Home library Current library Shelving location Date acquired Cataloger Shelving control number Total Checkouts Date last seen Price effective from Koha item type
    Library of Congress Classification     Meru University Meru University Open Shelves 09/09/2022 Mercy Musungu     09/09/2022 09/09/2022 Article


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